neoral® (cyclosporine) oral solution (100 mg/ml) (Novartis)
90
Structured Review
Novartis
neoral® (cyclosporine) oral solution (100 mg/ml)
Neoral® (Cyclosporine) Oral Solution (100 Mg/Ml), supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/neoral® (cyclosporine) oral solution (100 mg/ml)/product/Novartis
Average 90 stars, based on 1 article reviews
Neoral® (Cyclosporine) Oral Solution (100 Mg/Ml), supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/neoral® (cyclosporine) oral solution (100 mg/ml)/product/Novartis
Average 90 stars, based on 1 article reviews
neoral® (cyclosporine) oral solution (100 mg/ml) - by Bioz Stars,
2026-02
90/100 stars
Images
1) Product Images from "Development and validation of an LC-MS/MS method for highly concentrated tacrolimus and cyclosporine samples prepared from pharmaceutical products to assess drug loss from feeding tubes"
Article Title: Development and validation of an LC-MS/MS method for highly concentrated tacrolimus and cyclosporine samples prepared from pharmaceutical products to assess drug loss from feeding tubes
Journal: Journal of Mass Spectrometry and Advances in the Clinical Lab
doi: 10.1016/j.jmsacl.2024.10.002
Figure Legend Snippet: Chromatograms from (A) the final tacrolimus suspension and (B) the final cyclosporine solutions prepared from pharmaceutical products, as well as the chromatograms of the lowest calibrator from the 6PLUS1® Calibrator Set for (C) tacrolimus and (D) cyclosporine.
Techniques Used: Suspension
Figure Legend Snippet: Results from accuracy assessment by measuring QC materials from the inter-day precision study. Measurements of cyclosporine were performed using the 6PLUS1® calibrator Set, the in-house calibrator Set, and the 6PLUS1® calibrator Set with the batch-specific correction factor.
Techniques Used:
Figure Legend Snippet: Results from accuracy assessment by measuring tacrolimus suspensions (n = 3) and cyclosporine solutions prepared from pharmaceutical products (n = 3). Measurements of cyclosporine were performed using the 6PLUS1® calibrator Set, the in-house calibrator Set, and the 6PLUS1® calibrator set with the batch-specific correction factor.
Techniques Used:
Figure Legend Snippet: Results from precision studies (inter-day and intra-day). Measurements of cyclosporine were performed using the 6PLUS1® calibrator set with the batch-specific correction factor.
Techniques Used:
Figure Legend Snippet: Results from the matrix dilution study. Final tacrolimus suspensions (n = 2) and final cyclosporine solutions (n = 2) were diluted to five different ratios before sample preparation and measurements. ISTD responses were documented, with mean responses and %CV calculated from ISTD responses from all five matrix diluted samples, and recovery calculated from each matrix diluted sample.
Techniques Used: Sample Prep
Figure Legend Snippet: Post-column infusion analysis with injected methanol (dashed lines) and final tacrolimus suspension (A) or prepared cyclosporine solution (B) prepared using a surrogate ISTD solution without isotope-labeled ISTD (solid lines). Isotope-labeled ISTD was infused and was used as a surrogate for each analyte. The highlighted regions represent where tacrolimus and cyclosporine are eluted.
Techniques Used: Injection, Suspension, Labeling
